CBD & THC Treatment & Dosing Guide
Evidence-based starting dosing ranges, cannabinoid ratios, and clinical trial citations. Formulated to help patients make informed decisions alongside their Haven Marijuana Doctor physician.
The information provided in this CBD and THC dosing guide is intended for educational purposes only and should not be considered medical advice. Individual responses to cannabis can vary significantly, and it is essential to consult with a qualified healthcare professional before starting or adjusting any cannabis treatment. This guide does not replace personalized medical advice or treatment plans tailored to your specific health needs.
Anxiety
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
2.5-5 mg THC, as needed
Clinical Notes
Higher doses of THC may increase anxiety in some individuals. Start with low microdoses and prioritize high-CBD formulations.
Evidence Literature
Blessing, E. E., Steenkamp, M. M., Manzanares, J., & Marmar, C. R. (2015). Cannabidiol as a Potential Treatment for Anxiety Disorders. Neurotherapeutics, 12(4), 825-836.
Chronic Pain
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
5-10 mg THC, as needed
Clinical Notes
Start low and increase gradually based on tolerance. A 1:1 or 2:1 CBD:THC ratio often delivers optimal sustained analgesic relief.
Evidence Literature
National Academies of Sciences, Engineering, and Medicine. (2017). The Health Effects of Cannabis and Cannabinoids.
Cancer (pain management)
Recommended CBD Dose
50-100 mg CBD, taken 1-2 times daily
Recommended THC Dose
10-20 mg THC, taken as needed
Clinical Notes
THC can help with pain and nausea associated with chemotherapy and radiation treatment. High-CBD supports cellular comfort.
Evidence Literature
Tversky, F. (2015). Cannabinoids for cancer pain management. Journal of Pain & Palliative Care Pharmacotherapy, 29(3), 143-150.
Crohn's Disease
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
5-10 mg THC, as needed
Clinical Notes
Both CBD and THC can help manage inflammation and pain throughout the gastrointestinal tract and digestive lining.
Evidence Literature
Naftali, T., et al. (2013). Cannabis for the treatment of Crohn's disease. European Journal of Gastroenterology & Hepatology, 25(2), 202-206.
Depression
Recommended CBD Dose
20-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
2.5-10 mg THC, as needed
Clinical Notes
THC can enhance mood, but should be used cautiously. Low-dose daytime tinctures promote balanced cerebral blood flow without sedative heaviness.
Evidence Literature
Crippa, J. A., et al. (2009). Cannabidiol, a non-psychoactive cannabinoid, increases cerebral blood flow in humans. Psychopharmacology, 205(2), 207-216.
Epilepsy
Recommended CBD Dose
10-25 mg CBD, taken 1-3 times daily
Recommended THC Dose
1-5 mg THC, as needed
Clinical Notes
Higher CBD doses have been shown to be effective in seizure control. Consult your neurologist prior to modifying anti-epileptic medications.
Evidence Literature
Devinsky, O., Marsh, E., Friedman, D., et al. (2017). Cannabidiol in patients with treatment-resistant epilepsy: an open-label interventional trial. The Lancet Neurology, 16(3), 223-230.
Fibromyalgia
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
2.5-10 mg THC, as needed
Clinical Notes
Combination therapy may provide the best symptom relief for widespread musculoskeletal tenderness and daytime fatigue.
Evidence Literature
Miller, S. C., & Rosen, S. D. (2018). The use of cannabis in treating fibromyalgia. Journal of Clinical Psychology, 74(7), 1167-1175.
Insomnia
Recommended CBD Dose
30-50 mg CBD, taken before bedtime
Recommended THC Dose
2.5-5 mg THC, as needed
Clinical Notes
THC may enhance sleep onset, while CBD can reduce sleep disturbances and nocturnal awakenings. Take 30-45 minutes before sleep.
Evidence Literature
Babson, K. A., Sottile, J., & Morabito, D. (2017). Cannabis, Cannabinoids, and Sleep: A Review of the Evidence. Current Psychiatry Reports, 19(4).
Multiple Sclerosis (spasticity)
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
5-10 mg THC, as needed
Clinical Notes
THC may help reduce painful muscle spasticity, stiffness, and hyperreflexia in limbs.
Evidence Literature
Zajicek, J. P., Hobart, J. C., & Petty, R. (2012). Cannabinoids in multiple sclerosis (CAMS) study: a randomized, controlled trial. Lancet, 370(1379-1387).
Neuropathy
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
2.5-5 mg THC, as needed
Clinical Notes
CBD may help reduce nerve pain, while THC can provide additional relief for sharp, burning peripheral sensory disturbances.
Evidence Literature
Taylor, L., et al. (2016). Cannabis and cannabinoids in the management of neuropathic pain. Cochrane Database of Systematic Reviews.
PTSD
Recommended CBD Dose
25-60 mg CBD, taken 1-2 times daily
Recommended THC Dose
5-10 mg THC, as needed
Clinical Notes
Consider using THC in lower doses to avoid exacerbating anxiety while assisting with night terrors and hyperarousal.
Evidence Literature
Wilkins, K. (2020). The effects of cannabis on PTSD. Journal of Cannabis Research, 2(1), 1-7.
Post-Surgical Recovery
Recommended CBD Dose
25-50 mg CBD, taken 1-2 times daily
Recommended THC Dose
5-10 mg THC, as needed
Clinical Notes
May help with postoperative pain management and reduce localized tissue inflammation while tapering off opioids.
Evidence Literature
Schreiber, G., et al. (2019). Cannabinoids in the management of postoperative pain: a review. Pain Physician, 22(4), 325-332.
Rheumatoid Arthritis
Recommended CBD Dose
20-40 mg CBD, taken 1-2 times daily
Recommended THC Dose
2.5-5 mg THC, as needed
Clinical Notes
CBD may reduce inflammation and synovial swelling while THC alleviates joint stiffness and pain signals.
Evidence Literature
Walsh, Z., et al. (2016). Medical cannabis and mental health: a review of the literature. Cannabis and Cannabinoid Research, 1(1), 75-81.
The Haven MJD Clinical Dosing Philosophy: "Start Low, Go Slow"
Cannabinoid therapies possess a biphasic effect—meaning that lower doses often produce calming, analgesic responses while excessively high doses can induce anxiety or fatigue. Our certified Florida physicians tailor each patient's initial titration protocol with careful attention to existing prescription medications and metabolic tolerances.
1. Microdose First
Begin with minimal threshold doses for the first 3–5 days to observe how your endocannabinoid system responds.
2. Leverage CBD Buffers
Pairing CBD with THC mitigates unwanted psychoactivity, enhances anti-inflammatory outcomes, and stabilizes mood.
3. Adjust Delivery Routes
Inhalation delivers rapid onset (1–5 mins), sublingual tinctures provide steady daytime relief, and edibles offer sustained nocturnal sleep.